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p62 provides dual, reciprocal enhancing protection to RPE cells from environmental stress induced protein misfolding and aggregation
This review focuses on the role of p62 in linking the ubiquitin–proteasome system and autophagy pathway upon ubiquitinated protein degradation p62 TDP-43 CNS tumor: ACTH ATRX BRAF V600E © Copyright , Inc Click here for information on
เครดิตฟรี30 p62 serves as an adaptor protein for selective autophagy: when selective autophagic cargos such as damaged mitochondria appear in the cytoplasm, they are SQSTM1 , the gene coding for the p62 protein, spans about 16 kb and is located on chromosome 5 It is widely expressed and contains eight