Phospho-p62 MBL Life Sience -ASIA-

ALS-FTLD-linked mutations of SQSTM1p62 disrupt selective autophagy and NFE2L2NRF2 anti-oxidative stress pathway Publication Type, Journal

This review focuses on the role of p62 in linking the ubiquitin–proteasome system and autophagy pathway upon ubiquitinated protein degradation

p62com สล็อต p62com สล็อต p62 com In the absence of p62, STING failed to traffic to autophagy-associated vesicles Thus, DNA sensing induces the cGAS-STING pathway to activate

ทางเข้าp62 These two systems are linked via phosphorylation of the ubiquitin binding autophagy receptor protein p62SQSTM1 in the p62–Keap1–Nrf2 pathway